Yoshizumi K, Nagahata Y, Yamaguchi T, Kawakita N, Wada T, Yamamoto M, Saitoh Y
First Department of Surgery, Kobe University School of Medicine, Japan.
Nihon Geka Gakkai Zasshi. 1994 Sep;95(9):704-8.
A case of allergic granulomatous angitis (AGA) complicated with the perforation of the ileum was described. A 52-year-old male had suffered from bronchial asthma since 1990, and two years later he had severe attack of asthma and manifestation of systemic vasculitis. He was diagnosed a AGA with the symptom of vascultitis, history of asthma, and the abnormal hematological findings (WBC 13000/mm3, eosinophilia 11.1%, IgE 1290U/ml, RA 2+). The treatment with adrenal corticoid hormone was started. In April 1992, he complained of severe right lower abdominal pain. He was diagnosed the gastrointestinal perforation by the abdominal X-ray examination and emergency operation was performed. Two ileal perforations were found at the operation and the ileectomy was carried out. Only 11 cases of AGA complicated with the gastrointestinal perforation have ever been reported in Japan. The perforation occurred often at the small intestine and the poor prognosis was referred. The administration of adrenal corticoid hormone should be continued after operation.
报告了1例变应性肉芽肿性血管炎（AGA）合并回肠穿孔的病例。一名52岁男性自1990年起患有支气管哮喘，两年后哮喘严重发作并出现系统性血管炎表现。他因血管炎症状、哮喘病史及血液学检查异常（白细胞13000/mm³、嗜酸性粒细胞增多11.1%、免疫球蛋白E 1290U/ml、类风湿因子2+）被诊断为AGA。开始使用肾上腺皮质激素治疗。1992年4月，他主诉右下腹剧痛。经腹部X线检查诊断为胃肠道穿孔并进行了急诊手术。手术中发现两个回肠穿孔并实施了回肠切除术。在日本，仅有11例AGA合并胃肠道穿孔的病例报告。穿孔常发生于小肠且预后较差。术后应继续给予肾上腺皮质激素治疗。
