Frondaroli F, Di Leonardo A, Tella D, Khalig J G
Clinica Ginecologica ed Ostetrica, Università degli Studi di Chieti.
Minerva Ginecol. 1994 Oct;46(10):557-60.
To evaluate the prevalence of both sideropenic anemia and B-thalassemia in a group of pregnant women in the city of Chieti.
384 pregnant women who were examined at the obstetric clinic of Chieti University were introduced in the study. Serum levels of ferritin, transferrin, hemoglobin, plus blood cell count and hemoglobin electrophoresis were evaluated in each patient. Those laboratory parameters were also compared in a group of patients who early in gestation were given iron supplementation and a group of patients not supplemented.
beta-thalassemia showed a prevalence of 1.3% while sideropenic anemia had a prevalence of 10. The group of patients supplemented with iron early in gestation showed significantly better laboratory parameters than the group not supplemented.
Prevalence of beta-thalassemia in Chieti is inferior to the national mean prevalence. Iron supplementation early in pregnancy is associated with improved haematologic parameters in the third trimester.
评估基耶蒂市一组孕妇中铁缺乏性贫血和β地中海贫血的患病率。
384名在基耶蒂大学产科诊所接受检查的孕妇被纳入研究。对每位患者的血清铁蛋白、转铁蛋白、血红蛋白水平以及血细胞计数和血红蛋白电泳进行评估。还对一组在妊娠早期接受铁补充剂的患者和一组未补充铁的患者的这些实验室参数进行了比较。
β地中海贫血的患病率为1.3%，而铁缺乏性贫血的患病率为10%。妊娠早期补充铁的患者组的实验室参数明显优于未补充铁的患者组。
基耶蒂市β地中海贫血的患病率低于全国平均患病率。妊娠早期补充铁与孕晚期血液学参数的改善有关。
