Sukrat Bunyarit, Suwathanapisate Pranee, Siritawee Suparerk, Poungthong Thunyaporn, Phupongpankul Kornwika
Health Promotion Hospital, Regional Health Center 8, Nakhonsawan, Thailand.
J Med Assoc Thai. 2010 Jul;93(7):765-70.
To determine the prevalence of iron deficiency anemia in pregnant women and the prevalence of thalassemia in both the anemic and non-anemic group.
At the first antenatal visit, blood was obtained for complete blood count. If hemoglobin < 11 g/dl or hematocrit < 33%, serum ferritin was performed. The authors used definition of anemia from CDC and WHO to determine the prevalence of anemia in pregnant women. Iron deficiency anemia was defined by anemia from CDC or WHO criteria in accordance with serum ferritin less than 30 mg/L. Cases of abnormal thalassemia screening were followed by hemoglobin electrophoresis and polymerase chain reaction (PCR) for diagnosis of alpha thalassemia 1 (SEA and Thai-deletion type). The data was analyzed by descriptive fashion and presented as mean, percentage, and standard deviation.
Five hundred nineteen pregnant women were recruited. The prevalence of anemia from WHO (Hemoglobin < 11 g/ dl), WHO (Hematocrit < 33%), and CDC criteria were 14.1, 9.8, and 10.6% respectively. The prevalence of iron deficiency anemia was 6.0, 4.6, and 4.8% in the same order. The prevalence of thalassemia was 39.7% in the anemic group and 24.4% in the non-anemic group.
The WHO criteria (Hemoglobin < 11 g/dl) gave the highest prevalence of anemia and iron deficiency anemia during pregnancy (14.1% and 6.0%). The prevalence of thalassemia in the anemic group (39.7%) was higher than non-anemic group (24.4%).
确定孕妇缺铁性贫血的患病率以及贫血组和非贫血组地中海贫血的患病率。
在首次产前检查时采集血液进行全血细胞计数。如果血红蛋白<11 g/dl或血细胞比容<33%，则检测血清铁蛋白。作者采用美国疾病控制与预防中心（CDC）和世界卫生组织（WHO）的贫血定义来确定孕妇贫血的患病率。缺铁性贫血根据CDC或WHO标准定义为贫血且血清铁蛋白低于30 mg/L。对地中海贫血筛查异常的病例进行血红蛋白电泳和聚合酶链反应（PCR），以诊断α地中海贫血1（SEA和泰国缺失型）。数据采用描述性方式分析，并以均值、百分比和标准差表示。
招募了519名孕妇。WHO标准（血红蛋白<11 g/dl）、WHO标准（血细胞比容<33%）和CDC标准下的贫血患病率分别为14.1%、9.8%和10.6%。缺铁性贫血患病率依次为6.0%、4.6%和4.8%。贫血组地中海贫血患病率为39.7%，非贫血组为24.4%。
WHO标准（血红蛋白<11 g/dl）得出的孕期贫血和缺铁性贫血患病率最高（分别为14.1%和6.0%）。贫血组地中海贫血患病率（39.7%）高于非贫血组（24.4%）。
