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[来自埃塞俄比亚的移民中的甲状腺功能障碍和甲状腺肿]

[Thyroid dysfunction and goiter among immigrants from Ethiopia].

作者信息

Luboshitzky R, Dgani Y, Atar S, Qupty G, Rakover Y, Tamir A, Flatau E

机构信息

Endocrine Institute, Central Emek Hospital, Afula.

出版信息

Harefuah. 1994 Nov 1;127(9):289-93, 360.

PMID:7843650
Abstract

1131 immigrants from Gonder, Ethiopia were surveyed a year after arrival in Israel. The overall prevalence of goiter was 46.1%; the lowest rates (6.7%) were in infants (aged 1-2 years) and the peak prevalence in males was 56.7% (in those aged 12-14 years) and in females, 77.7% (in those aged 35-40). A significant decrease in goiter prevalence was observed after the age of 60 for both men (7.2%) and women (35%). The prevalence of hypothyroidism was 1.1%, 2% in children and 0.2% in adults. That of hyperthyroidism was 1.7%, 0.8% in children and 2.4% in adults. The high prevalence of goiter and hyperthyroidism with low prevalence of hypothyroidism probably resulted from the combined effects of food goitrogens and iodine deficiency in Ethiopia, with the latter playing only a minor role. Neither factor was in effect after arrival in Israel. Genetic and hormonal factors may contribute to the low prevalence of both goiter and hypothyroidism in the adult males. In view of the high prevalence of hyperthyroidism, iodine enrichment is not recommended for Ethiopian immigrants.

摘要

对1131名来自埃塞俄比亚贡德尔的移民抵达以色列一年后进行了调查。甲状腺肿的总体患病率为46.1%;最低患病率(6.7%)出现在婴儿(1 - 2岁)中,男性患病率峰值为56.7%(12 - 14岁人群),女性为77.7%(35 - 40岁人群)。60岁以后,男性(7.2%)和女性(35%)的甲状腺肿患病率均显著下降。甲状腺功能减退症的患病率为1.1%,儿童为2%,成人为0.2%。甲状腺功能亢进症的患病率为1.7%,儿童为0.8%,成人为2.4%。甲状腺肿和甲状腺功能亢进症的高患病率以及甲状腺功能减退症的低患病率可能是埃塞俄比亚食物中致甲状腺肿物质和碘缺乏共同作用的结果,其中碘缺乏起的作用较小。抵达以色列后这两个因素都不再起作用。遗传和激素因素可能导致成年男性甲状腺肿和甲状腺功能减退症的患病率较低。鉴于甲状腺功能亢进症的高患病率,不建议对埃塞俄比亚移民进行碘强化。

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