Baral N, Lamsal M, Koner B C, Koirala S
Department of Biochemistry, BP Koirala Institute of Health Sciences, Dharan, Nepal.
Southeast Asian J Trop Med Public Health. 2002 Sep;33(3):638-41.
Nepal lies in an area of endemic iodine deficiency. Thyroid dysfunction, along with a higher than average prevalence of goiter, is a major public health problem among the local population. The present study was undertaken to investigate the prevalence of thyroid dysfunction among the hill and terai (low land) castes of eastern Nepal that attended the thyroid clinic at the BP Koirala Institute of Health Sciences (BPKIHS), Dharan. A total of 599 cases were studied during a single year. The distribution of hyperthyroid and hypothyroidism was 13.68% and 17.19% respectively. The majority of the thyroid dysfunction was seen in the 21-40 year age group. The prevalence of hypothyroidism was slightly higher among terai castes (17.66%) when compared with hill castes (15.17%). There was a similar distribution of thyroid dysfunction among the male and female populations of the goitrous subjects (n=157), most were euthyroid (58.59%); hyperthyroidism affected (27.38%). Since, it was a hospital-based study, the prevalence of thyroid dysfunction may not be applicable to the general population. Extensive field-based countrywide epidemiological studies are necessary to provide data about thyroid dysfunction in the community.
尼泊尔位于碘缺乏病流行地区。甲状腺功能障碍以及甲状腺肿患病率高于平均水平，是当地人群中的一个主要公共卫生问题。本研究旨在调查在达兰的BP柯伊拉腊健康科学研究所（BPKIHS）甲状腺诊所就诊的尼泊尔东部山区和特莱（低地）种姓人群中甲状腺功能障碍的患病率。在一年时间里共研究了599例病例。甲状腺功能亢进和甲状腺功能减退的分布分别为13.68%和17.19%。大多数甲状腺功能障碍出现在21至40岁年龄组。与山区种姓（15.17%）相比，特莱种姓中甲状腺功能减退的患病率略高（17.66%）。在甲状腺肿患者（n = 157）的男性和女性人群中，甲状腺功能障碍的分布相似，大多数人甲状腺功能正常（58.59%）；甲状腺功能亢进患者占（27.38%）。由于这是一项基于医院的研究，甲状腺功能障碍的患病率可能不适用于一般人群。需要进行广泛的全国性实地流行病学研究，以提供有关社区甲状腺功能障碍的数据。
