Lua A C, Chu D K, Vlastelica D
Miles Inc., Diagnostic Division, Tarrytown, NY 10591.
Ther Drug Monit. 1994 Oct;16(5):495-8. doi: 10.1097/00007691-199410000-00009.
We report the determination of digoxin concentration in serum with Microgenics Cedia digoxin reagents on the Technicon CHEM 1. The Technicon CHEM 1 clinical chemistry analyzer has a throughput of 720 tests per hour and uses only 7 microliters each of two reagents. A 100 test kit can perform 2,640 tests. The within-run coefficient of variation (CV) range is 2.3-0.9% and the total CV is 6.3-2.9% at concentrations tested ranging from 1.10 to 2.94 ng/ml. The results of the Technicon CHEM 1 (y) assay correlated well with those by the Technicon RA 1000 system (x) with 31 clinical serum samples (y = -0.03 + 1.11x, r = 0.96). We concluded that the Cedia digoxin assay on the Technicon CHEM 1 provides a very cost-effective, precise, rapid, and accurate means to determine digoxin concentration in serum.
我们报告了使用Technicon CHEM 1上的Microgenics Cedia地高辛试剂测定血清中地高辛浓度的情况。Technicon CHEM 1临床化学分析仪每小时可进行720次检测，且两种试剂每种仅使用7微升。一个100次检测试剂盒可进行2640次检测。在所检测的1.10至2.94纳克/毫升浓度范围内，批内变异系数（CV）范围为2.3 - 0.9%，总CV为6.3 - 2.9%。对于31份临床血清样本，Technicon CHEM 1（y）检测结果与Technicon RA 1000系统（x）的结果相关性良好（y = -0.03 + 1.11x，r = 0.96）。我们得出结论，Technicon CHEM 1上的Cedia地高辛检测法为测定血清中地高辛浓度提供了一种非常经济高效、精确、快速且准确的方法。
