Lin C H, Thompson C A, Forscher P
Department of Biology, Yale University, New Haven, Connecticut 06520-8103.
Curr Opin Neurobiol. 1994 Oct;4(5):640-7. doi: 10.1016/0959-4388(94)90004-3.
Recent studies have implicated cytoskeletal dynamics as an important component in directing neuronal outgrowth. By using modern imaging techniques to observe the kinetics of individual cytoskeletal elements in living cells, these results have converged upon a common theme: functional coupling between the intracellular cytoskeleton and extracellular substrates, and regulation thereof, appears to be crucial in controlling neuronal migration.
最近的研究表明，细胞骨架动力学是引导神经元生长的重要组成部分。通过使用现代成像技术观察活细胞中单个细胞骨架元件的动力学，这些研究结果都指向了一个共同的主题：细胞内细胞骨架与细胞外基质之间的功能耦合及其调控，在控制神经元迁移中似乎至关重要。
