Oxynoid O E, Sydliarov D P, Aprosin Y D, Obraztsov V V
Research Center, NIZAR Pharm.Co., Moscow, Russia.
Artif Cells Blood Substit Immobil Biotechnol. 1994;22(4):1331-6. doi: 10.3109/10731199409138834.
Localization and accumulation of perfluorochemicals (PFCs) in the skin and internal organs of rats after prolonged surface application of the concentrated PFC emulsion, fluorogel, have been studied by electron microscopy and gas-chromatography. The PFC concentration in skin was about 0.03-0.04 mg per 1 g of tissue. Few aggregates of emulsion particles were detected in derma. The oxygen-dependent favorable effect of fluorogel treatment of thermic burned skin and wound surface was found.
通过电子显微镜和气相色谱法,研究了大鼠长时间表面涂抹浓缩全氟化合物(PFC)乳液氟凝胶后,PFC在皮肤和内部器官中的定位与蓄积情况。皮肤中PFC的浓度约为每1克组织0.03 - 0.04毫克。在真皮中检测到少量乳液颗粒聚集体。发现氟凝胶对热烧伤皮肤和创面的治疗具有氧依赖性的有益效果。