Chen W R, Adams R L, Heaton S, Dickey D T, Bartels K E, Nordquist R E
Oklahoma School of Science and Mathematics, Oklahoma City 73104.
Cancer Lett. 1995 Jan 6;88(1):15-9. doi: 10.1016/0304-3835(94)03609-m.
A diode laser was used to irradiate tumor tissue, with indocyanine green as the chromophore. The 808-nm wavelength radiation falls within the absorption peak of the chromophore (about 780 nm). The preliminary results in this report revealed clear and significant coupling of this laser and indocyanine green in laser-tissue photothermal interaction. The chromophore targeted tissue showed laser damage while peripheral tissues remained intact. Without the chromophore, this laser inflicted no apparent tissue damage in the non-contact mode with irradiance up to 1755 J/cm2.
使用二极管激光照射肿瘤组织，以吲哚菁绿作为发色团。808纳米波长的辐射落在发色团的吸收峰范围内（约780纳米）。本报告中的初步结果显示，在激光与组织的光热相互作用中，这种激光与吲哚菁绿之间存在明显且显著的耦合。发色团靶向的组织出现激光损伤，而周边组织保持完整。在没有发色团的情况下，这种激光在非接触模式下，辐照度高达1755 J/cm²时不会造成明显的组织损伤。
