De Los Santos R, Lin Y T, Corpron R E, Beltran E D, Strachan D S, Landry P A
School of Dentistry, University of Michigan, Ann Arbor 48103-1078.
Caries Res. 1994;28(6):441-6. doi: 10.1159/000262018.
The in situ remineralization of early root surface lesions was studied using a fluoride-releasing device (FRD) or a fluoride chewing gum. Root specimens with subsurface lesions were mounted in removable lower appliances in 6 adult subjects. Test groups chewed five sticks/day (0.1 mg F/stick) or one FRD (0.5 mg F/day release rate) was mounted in the midline of the appliance. A fluoride-free dentifrice was used three times/day for each 21-day control and the two test regimens. Separate root lesions were used to measure fluoride uptake or changes in mineral content by quantitative microradiography. Comparable values for percent remineralization for both FRDs and F gum were higher than controls, and the F uptake for FRDs exceeded both the F gum and controls (p = 0.05).
使用一种释氟装置（FRD）或含氟口香糖对早期牙根表面病变的原位再矿化进行了研究。在6名成年受试者中，将有牙本质表层下病变的牙根标本安装在可移除的下颌矫治器中。试验组每天咀嚼5根口香糖（每根含0.1毫克氟），或在矫治器中线处安装一个FRD（每天释氟率0.5毫克）。在为期21天的对照期以及两种试验方案中，均每天使用不含氟的牙膏3次。通过定量显微放射照相术，使用单独的牙根病变来测量氟摄取量或矿物质含量的变化。FRD和含氟口香糖的再矿化百分比的可比数值均高于对照组，并且FRD的氟摄取量超过了含氟口香糖组和对照组（p = 0.05）。
