Mergo P J, Ros P R, Buetow P C, Buck J L
Department of Radiology, University of Florida College of Medicine, Gainesville 32610-0374.
Radiographics. 1994 Nov;14(6):1291-307. doi: 10.1148/radiographics.14.6.7855342.
Cross-sectional imaging is playing an increasing role in diagnosis of diffuse liver diseases because it clarifies, in many cases, the overlap in clinical and laboratory manifestations often present in diffuse hepatic processes and thus may eliminate the need for a biopsy. Advances in cross-sectional imaging, particularly in magnetic resonance (MR) imaging, enable further characterization of hepatic parenchymal and architectural changes, allowing closer correlation with underlying pathologic changes. Advanced imaging techniques can be used to characterize a variety of metabolic, vascular, toxic, infectious, and neoplastic diffuse liver diseases. These include more common entities such as cirrhosis, Budd-Chiari syndrome, hemochromatosis, Wilson disease, fatty change, and diffuse neoplastic disease (hepatocellular carcinoma, metastasis, and lymphoma) and uncommon entities such as schistosomiasis, sarcoidosis, and amyloidosis. Correlation of computed tomographic and MR imaging findings with underlying pathologic features is helpful in understanding the gamut of diffuse diseases of the liver.
横断面成像在弥漫性肝病的诊断中发挥着越来越重要的作用，因为在许多情况下，它能明确弥漫性肝脏病变中临床和实验室表现常常存在的重叠情况，从而可能无需进行活检。横断面成像技术的进步，尤其是磁共振（MR）成像技术的进步，能够进一步明确肝实质和结构变化的特征，使我们能够更紧密地将其与潜在的病理变化相关联。先进的成像技术可用于明确各种代谢性、血管性、中毒性、感染性和肿瘤性弥漫性肝病的特征。这些疾病包括更常见的病症，如肝硬化、布加综合征、血色素沉着症、威尔逊病、脂肪变性以及弥漫性肿瘤性疾病（肝细胞癌、转移瘤和淋巴瘤），还有不常见的病症，如血吸虫病、结节病和淀粉样变性。将计算机断层扫描和MR成像结果与潜在的病理特征相关联，有助于我们理解肝脏弥漫性疾病的全貌。
