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识别猪B细胞上分化抗原的单克隆抗体。

Monoclonal antibodies recognising differentiation antigens on porcine B cells.

作者信息

Denham S, Shimizu M, Bianchi A T, Zwart R J, Carr M M, Parkhouse R M

机构信息

AFRC Institute for Animal Health, Pirbright Laboratory, Woking, UK.

出版信息

Vet Immunol Immunopathol. 1994 Oct;43(1-3):259-67. doi: 10.1016/0165-2427(94)90146-5.

DOI:10.1016/0165-2427(94)90146-5
PMID:7856057
Abstract

Nineteen monoclonal antibodies (mAbs) submitted to the porcine CD Workshop were analysed on porcine B cells from different lymphoid tissues by flow cytometry and immunohistochemistry. Six mAbs only bound to pig B cells and three of these were assigned cluster numbers, 76-7-4 (No. 001):CD1, K231-3B2 (No. 027):CD25 and CC51 (No. 100):CD21. Of the three remaining B cell positive mAbs, one was assigned to a swine cluster, CC55 (No. 101):SWC7, a second, LIG4 (No. 123), recognised cell surface IgM and the third, MUC106A (No. 072), remained unassigned.

摘要

将19种单克隆抗体(mAb)提交给猪CD研讨会,通过流式细胞术和免疫组织化学对来自不同淋巴组织的猪B细胞进行分析。6种mAb仅与猪B细胞结合,其中3种被赋予簇编号,76 - 7 - 4(编号001):CD1、K231 - 3B2(编号027):CD25和CC51(编号100):CD21。在其余3种B细胞阳性mAb中,一种被归入猪簇,CC55(编号101):SWC7,第二种,LIG4(编号123),识别细胞表面IgM,第三种,MUC106A(编号072),仍未被归类。

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