Phillips P P, Olsen K D
Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota.
Ann Otol Rhinol Laryngol. 1995 Feb;104(2):100-4. doi: 10.1177/000348949510400203.
The records of 126 patients with recurrent pleomorphic adenoma of the parotid gland treated at our institution from 1965 to 1985 were retrospectively reviewed. Multiple variables were analyzed to determine tumor behavior and treatment results. Of the study patients, 61% were female and 39% male, with a mean age of 35.6 years at the time of treatment at our institution. The average follow-up period was 14.5 years. Tumor recurrence was 32.5% after one operation at our institution, 7.1% after two operations, and 1.6% after three. Malignant disease occurred in 9 (7.1%) patients. After all surgical procedures, partial facial nerve paralysis was noted in 13.5% and total paralysis in 5.5%. These results suggest low morbidity and good success in tumor eradication with an aggressive surgical approach.
对1965年至1985年在我院接受治疗的126例复发性腮腺多形性腺瘤患者的记录进行了回顾性研究。分析了多个变量以确定肿瘤行为和治疗结果。在研究患者中,61%为女性,39%为男性,在我院接受治疗时的平均年龄为35.6岁。平均随访期为14.5年。在我院进行一次手术后肿瘤复发率为32.5%,两次手术后为7.1%,三次手术后为1.6%。9例(7.1%)患者发生恶性病变。在所有外科手术后,13.5%的患者出现部分面神经麻痹,5.5%的患者出现完全麻痹。这些结果表明,积极的手术方法发病率低且肿瘤根除成功率高。