ND1，一种新的中性粒细胞抗原。
ND1, a new neutrophil granulocyte antigen.
作者信息
Verheugt F W, von dem Borne A E, von Noord-Bokhorst J C, Nijenhuis L E, Engelfriet C P
出版信息
Vox Sang. 1978 Jul-Aug;35(1-2):13-7. doi: 10.1111/j.1423-0410.1978.tb02895.x.
The serum of 2 patients suffering from autoimmune neutrophil granulocytopenia contained autoantibodies that were directed against a new granulocyte-specific antigen. Genetic analysis showed that this new antigen was not correlated with the already known neutrophil antigens, NA1, NA2, NB1, NC1 or 9a. This was studied in a four-generation family. In the Dutch population the frequency of the antigen, tentatively called ND1, is 98.5% (n = 67), pointing to a gene frequency of 0.88.
两名患有自身免疫性中性粒细胞减少症患者的血清中含有针对一种新的粒细胞特异性抗原的自身抗体。基因分析表明，这种新抗原与已知的中性粒细胞抗原NA1、NA2、NB1、NC1或9a不相关。这是在一个四代家族中进行研究的。在荷兰人群中，这种暂时称为ND1的抗原频率为98.5%（n = 67），表明基因频率为0.88。
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