Iakovchenko V A, Uteshev B S
Zh Mikrobiol Epidemiol Immunobiol. 1976(3):100-4.
The influence of the donor priming upon the recipient's immune response under conditons of syngenic transfer of nucleated cells of the bone marrow, thymus, spleen to the lethally irradiated recipients was studied, the recipients being immunized with sheep erythrocytes. A fall of total number of antibody-forming cells was observed in the recipients in priming. The number of hemolytic foci was increased the first day after priming in case of injection of the bone marrow cells from the intact donors and of the thymus cells from the immunized donors. On the third day of the experiment the number of these foci was three time less in comparison with the control. An increase of the hemolytic foci was discovered in the syngenic transfer of splenic cells affected by priming.
研究了在将骨髓、胸腺、脾脏有核细胞同基因转移给致死性照射受体的条件下，供体预处理对受体免疫反应的影响，受体用绵羊红细胞进行免疫。在预处理的受体中观察到抗体形成细胞总数下降。在注射来自未受处理供体的骨髓细胞和来自经免疫供体的胸腺细胞的情况下，预处理后第一天溶血灶数量增加。在实验的第三天，与对照组相比，这些病灶的数量减少了三分之二。在受预处理影响的脾细胞同基因转移中发现溶血灶增加。
