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A simple radioassay for dihydrofolate synthetase activity in Escherichia coli and its application to an inhibition study of new pteroate analogs.

作者信息

Ho R I, Corman L, Ho J, Nair M G

出版信息

Anal Biochem. 1976 Jun;73(2):493-500. doi: 10.1016/0003-2697(76)90199-8.

DOI:10.1016/0003-2697(76)90199-8
PMID:786066
Abstract
摘要

相似文献

1
A simple radioassay for dihydrofolate synthetase activity in Escherichia coli and its application to an inhibition study of new pteroate analogs.一种用于检测大肠杆菌中二氢叶酸合成酶活性的简单放射分析方法及其在新型蝶酸类似物抑制研究中的应用。
Anal Biochem. 1976 Jun;73(2):493-500. doi: 10.1016/0003-2697(76)90199-8.
2
A simple radioassay for dihydrofolate synthetase activity in Escherichia coli and its application to an inhibition study of new pteroate analogs.
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3
Inhibition of dihydrofolate synthetase by folate, homofolate, pteroate and homopteroate and their reduced forms.叶酸、高叶酸、蝶酸和高蝶酸及其还原形式对二氢叶酸合成酶的抑制作用。
Biochim Biophys Acta. 1976 Feb 13;422(2):419-26. doi: 10.1016/0005-2744(76)90152-2.
4
Homology of Escherichia coli B glutathione synthetase with dihydrofolate reductase in amino acid sequence and substrate binding site.大肠杆菌B谷胱甘肽合成酶与二氢叶酸还原酶在氨基酸序列和底物结合位点上的同源性。
J Biochem. 1987 Jan;101(1):207-15. doi: 10.1093/oxfordjournals.jbchem.a121893.
5
Inhibition of dihydrofolate synthetase from Neisseria gonorrhoeae by dihydropteroate and dihydrofolate derivatives.二氢蝶酸酯和二氢叶酸衍生物对淋病奈瑟菌二氢叶酸合成酶的抑制作用。
Chem Biol Interact. 1981 Sep;36(3):369-73. doi: 10.1016/0009-2797(81)90079-x.
6
Relation between structure of sulphonamides and inhibition of H2-pteroate synthesis in Escherichia coli.磺胺类药物的结构与大肠杆菌中H2-蝶酸合成抑制之间的关系。
J Pharm Pharmacol. 1974 Apr;26(4):228-34. doi: 10.1111/j.2042-7158.1974.tb09263.x.
7
The formation of H2-pteroate analogs from PABA-antagonists in a cell-free system of E. coli.在大肠杆菌无细胞系统中由对氨基苯甲酸拮抗剂形成H2-蝶酸类似物。
Arch Int Pharmacodyn Ther. 1973 Dec;206(2):272-81.
8
A simplified radioassay method of dihydropteroate synthetase activity in Escherichia coli and its application for an inhibition study of p-aminobenzoi acid derivatives.
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Sulfonamide structure-activity relationships in a cell-free system. 2. Proof for the formation of a sulfonamide-containing folate analog.无细胞体系中的磺胺类构效关系。2. 含磺胺类叶酸类似物形成的证据。
J Med Chem. 1974 Jan;17(1):23-8. doi: 10.1021/jm00247a006.
10
Nutritional requirements for folate compounds and some enzyme activities involved in the folate biosynthesis.
J Nutr Sci Vitaminol (Tokyo). 1977;23(2):95-100. doi: 10.3177/jnsv.23.95.

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Targeting purine and pyrimidine metabolism in human apicomplexan parasites.针对人类顶复门寄生虫中的嘌呤和嘧啶代谢
Curr Drug Targets. 2007 Jan;8(1):31-47. doi: 10.2174/138945007779315524.
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Comparative folate metabolism in humans and malaria parasites (part II): activities as yet untargeted or specific to Plasmodium.人类与疟原虫的叶酸代谢比较（第二部分）：尚未成为靶点或疟原虫特有的活性
Trends Parasitol. 2005 Jul;21(7):334-9. doi: 10.1016/j.pt.2005.05.008.
3
Characterization and inhibition of dihydrofolate synthetase from Neisseria gonorrhoeae.
Mol Cell Biochem. 1984;59(1-2):165-71. doi: 10.1007/BF00231312.