Figgs L W, Dosemeci M, Blair A
Occupational Studies Section, National Cancer Institute, Bethesda, Maryland 20892-7364.
J Occup Med. 1994 Nov;36(11):1210-21. doi: 10.1097/00043764-199411000-00007.
This cancer surveillance investigation uses death certificates from 24 states for the period 1984-1989 to identify multiple myeloma and occupation associations and to stimulate hypotheses. A case-control study of multiple myeloma was created from 3,159,417 certificates in which 12,148 male and female cases were frequency matched by age, race, and gender with five controls per case. We screened 231 industries and 509 occupations. Women demonstrated significant excess risk among managers and administrators, post-secondary teachers, elementary teachers, social workers, other sales workers, waitresses, and hospital maids. Men showed significant risks among computer system scientists, veterinarians, elementary teachers, authors, engineering technicians, general office supervisors, insurance adjusters, barbers, electronic repairers, supervisors of extracting industries, production supervisors, photoengravers, and grader/dozer operators. Men and women elementary school teachers demonstrated the most consistent, statistically significant increased risk of multiple myeloma.
这项癌症监测调查利用1984年至1989年期间24个州的死亡证明来确定多发性骨髓瘤与职业之间的关联，并激发相关假设。从3159417份证明中开展了一项多发性骨髓瘤病例对照研究，其中12148例男性和女性病例按年龄、种族和性别与每例病例5名对照进行频率匹配。我们筛查了231个行业和509种职业。女性在经理和行政人员、高等院校教师、小学教师、社会工作者、其他销售人员、女服务员和医院女仆中显示出显著的超额风险。男性在计算机系统科学家、兽医、小学教师、作家、工程技术人员、办公室主管、保险理赔员、理发师、电子维修人员、采掘行业主管、生产主管、照相制版工和平地机/推土机操作员中显示出显著风险。男性和女性小学教师患多发性骨髓瘤的风险增加最为一致且具有统计学意义。
