Robinson C F, Walker J T
Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA.
Am J Ind Med. 1999 Jul;36(1):186-92. doi: 10.1002/(sici)1097-0274(199907)36:1<186::aid-ajim26>3.0.co;2-h.
Our study examined cancer mortality before the age of 65 for women employed in the fastest growing and/or traditionally female occupations. Analysis of mortality data from 28 U.S. states for 1984-1995 revealed elevated proportionate cancer mortality ratios (PCMRs). The highest PCMRs observed were thyroid cancer among health aides, lymphatic and multiple myeloma among computer programmers, and brain cancer among actresses and directresses. Some of the excess mortality occurred for occupations that have been previously cited. These included elevated breast and ovarian cancer among teachers, Hodgkin's disease among hairdressers and cosmetologists, and thyroid cancer among health aides and therapists. A few of the associations were new, i.e., had not been previously observed. These included cancer of the connective tissue and lymphatic system among computer programmers, ovarian cancer and leukemia among secretaries, and lymphatic cancer and multiple myeloma among child care workers. These findings should be further investigated with epidemiologic and environmental studies.
我们的研究调查了受雇于增长最快和/或传统女性职业的女性在65岁之前的癌症死亡率。对1984年至1995年美国28个州的死亡率数据进行分析后发现,按比例计算的癌症死亡率(PCMR)有所升高。观察到的最高PCMR分别是健康护理员中的甲状腺癌、计算机程序员中的淋巴癌和多发性骨髓瘤,以及女演员和女导演中的脑癌。一些超额死亡率出现在之前提到过的职业中。这些职业包括教师中乳腺癌和卵巢癌发病率升高、美发师和美容师中霍奇金淋巴瘤发病率升高,以及健康护理员和治疗师中甲状腺癌发病率升高。有一些关联是新发现的,即之前未曾观察到。这些关联包括计算机程序员中结缔组织和淋巴系统癌症、秘书中卵巢癌和白血病,以及儿童保育员中淋巴癌和多发性骨髓瘤。这些发现应通过流行病学和环境研究作进一步调查。