Hess R F, Field D J
McGill Vision Research, Department of Ophthalmology, McGill University, Montreal, Quebec, Canada.
Vision Res. 1994 Dec;34(24):3397-406. doi: 10.1016/0042-6989(94)90073-6.
We examine two competing explanations for the spatial localization deficit in human strabismic amblyopia, namely neural undersampling and uncalibrated neural disarray. An undersampling hypothesis would predict an associated deficit for contrast discrimination for which we find no evidence in strabismic amblyopia. A neural disarray hypothesis would predict an associated deficit in the degree to which stimuli appear spatially distorted. We find evidence for such a deficit in strabismic amblyopia. We propose that the spatial deficit in strabismic amblyopia is due to a filter-based distortion which is unable to be re-calibrated by higher visual centres.
我们研究了对人类斜视性弱视空间定位缺陷的两种相互竞争的解释，即神经采样不足和未校准的神经紊乱。采样不足假说预测对比敏感度会有相关缺陷，但我们在斜视性弱视中未发现此证据。神经紊乱假说预测刺激在空间上出现扭曲的程度会有相关缺陷。我们在斜视性弱视中发现了这种缺陷的证据。我们提出，斜视性弱视的空间缺陷是由于基于滤波器的失真，而高级视觉中枢无法对其进行重新校准。
