Vataeva L A, Egorova V V, Kassil' V G, Nikitina A A, Timofeeva N M
Zh Evol Biokhim Fiziol. 1994 Jul-Aug;30(4):532-40.
Studies have been made on the formation of the spectrum of digestive enzymes in the small intestine of weanling rats which were taken from lactating female and given semisynthetic food at the age of 17, 21 and 25 days. It was shown that the rate of general development and maturation of the digestive enzymes depends on the age of animals and the mode of their breeding (isolated or in a group of the same age). These factors significantly affect also the level of the activity and proximo-distal gradient of distribution of the following intestinal enzymes: lactase, sucrase, alkaline phosphatase, alanine aminopeptidase, glycyl-L-leucine dipeptidase, as well as the mass of the mucose and protein content of the small intestine.
对从哺乳期母鼠处获取、在17、21和25日龄时给予半合成食物的断奶幼鼠小肠中消化酶谱的形成进行了研究。结果表明，消化酶的总体发育和成熟速度取决于动物的年龄及其饲养方式（单独饲养或与同龄组一起饲养）。这些因素也显著影响以下肠道酶的活性水平和近端-远端分布梯度：乳糖酶、蔗糖酶、碱性磷酸酶、丙氨酸氨基肽酶、甘氨酰-L-亮氨酸二肽酶，以及小肠的黏液量和蛋白质含量。
