Kröger H, Jurvelin J, Arnala I, Penttilä K, Rask A, Vainio P, Alhava E
Department of Surgery, Kuopio University Hospital, Finland.
Acta Orthop Scand. 1995 Feb;66(1):47-52. doi: 10.3109/17453679508994639.
We determined broadband ultrasound attenuation (BUA) of the calcaneus, and bone mineral density (BMD) of the spine, proximal femur and radius in 137 healthy subjects (79 women and 58 men) and in 56 women with Colles' fracture. The repeated measurements on 9 healthy subjects indicated a short-term reproducibility (coefficient of variation) of 4 percent for BUA. There was a small (7 percent) but significant difference in BUA between normal men and women. The age-dependence in normal subjects was weak. When all the study subjects were pooled, modest correlations between BUA of the calcaneus and BMD at all measured skeletal sites were found (rs values 0.3-0.4). However, it was not possible to make an accurate prediction of the axial BMD, using BUA. BUA values were 13 percent lower in the wrist fracture patients than in the age-matched normals. In general, BUA could discriminate the fracture patients from normals as effectively as BMD. As suggested by the physical theory of ultrasound attenuation, our results support the idea that BUA reflects not only the bone density but also other factors related to the structural properties of bone.
我们测定了137名健康受试者（79名女性和58名男性）以及56名柯莱斯骨折女性的跟骨宽带超声衰减（BUA），以及脊柱、股骨近端和桡骨的骨密度（BMD）。对9名健康受试者的重复测量表明，BUA的短期重复性（变异系数）为4%。正常男性和女性之间的BUA存在微小（7%）但显著的差异。正常受试者中年龄依赖性较弱。当将所有研究对象合并时，发现跟骨的BUA与所有测量骨骼部位的BMD之间存在适度的相关性（rs值为0.3 - 0.4）。然而，使用BUA无法准确预测轴向BMD。腕部骨折患者的BUA值比年龄匹配的正常受试者低13%。总体而言，BUA能够像BMD一样有效地将骨折患者与正常受试者区分开来。正如超声衰减物理理论所表明的，我们的结果支持这样一种观点，即BUA不仅反映骨密度，还反映与骨结构特性相关的其他因素。
