de Leon J, Dadvand M, Canuso C, White A O, Stanilla J K, Simpson G M
Medical College of Pennsylvania, Eastern Pennsylvania Psychiatric Institute, Haverford.
Am J Psychiatry. 1995 Mar;152(3):453-5. doi: 10.1176/ajp.152.3.453.
The authors sought to determine whether smoking is related to schizophrenia or neuroleptic treatment.
Cigarette smoking was measured in all patients hospitalized at a state hospital (N = 360) and compared in relation to gender and diagnosis (schizophrenic versus nonschizophrenic).
The overall frequency of smoking was 79% (N = 284). Male schizophrenic patients had the highest frequency of smoking, followed by male nonschizophrenic patients, female schizophrenic patients, and female nonschizophrenic patients, respectively. Schizophrenia and polydipsia were associated with both smoking and heavy smoking.
After correction for other variables, schizophrenia appears to increase the risk of being both a smoker and a heavy smoker. There was a possible association between high doses of neuroleptics and smoking but only for nonschizophrenic patients.
作者试图确定吸烟是否与精神分裂症或抗精神病药物治疗有关。
对一家州立医院住院的所有患者（N = 360）进行吸烟情况测量，并根据性别和诊断（精神分裂症患者与非精神分裂症患者）进行比较。
吸烟的总体频率为79%（N = 284）。男性精神分裂症患者吸烟频率最高，其次分别是男性非精神分裂症患者、女性精神分裂症患者和女性非精神分裂症患者。精神分裂症和烦渴与吸烟及重度吸烟均有关联。
在对其他变量进行校正后，精神分裂症似乎会增加成为吸烟者和重度吸烟者的风险。高剂量抗精神病药物与吸烟之间可能存在关联，但仅针对非精神分裂症患者。
