Wong G W
Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories.
J Paediatr Child Health. 1994 Dec;30(6):490-1. doi: 10.1111/j.1440-1754.1994.tb00718.x.
Thirty-three southern Chinese children with insulin-dependent diabetes mellitus (IDDM) were studied. The patients had a mean follow-up of 5.2 years (range 1.2-8.2). The mean age of onset was 8.3 years (range 1.7-13.5). The mean duration of symptoms before diagnosis was 22 days. Ten patients (30%) presented with diabetic ketoacidosis at diagnosis. Only one patient (3%) was found to have thyroid microsomal antibodies and none was found to have hypothyroidism or hyperthyroidism. Incidence and prevalence were calculated from data recorded retrospectively and prospectively in a population-based registry of IDDM. The prevalence in 1991 and 1992 was 8.3 per 100,000 children under 15 years of age. The age-standardized incidence of IDDM was 1.7/100,000 per year with the 95% confidence interval of 1.2-2.4/100,000 per year for children under 15 years of age during the years 1986-93. The incidence for males was 1.1/100,000 per year and for females, 2.4/100,000 per year.
对33名患有胰岛素依赖型糖尿病（IDDM）的中国南方儿童进行了研究。这些患者的平均随访时间为5.2年（范围1.2 - 8.2年）。发病的平均年龄为8.3岁（范围1.7 - 13.5岁）。诊断前症状的平均持续时间为22天。10名患者（30%）在诊断时出现糖尿病酮症酸中毒。仅1名患者（3%）被发现有甲状腺微粒体抗体，未发现有甲状腺功能减退或甲状腺功能亢进的患者。发病率和患病率是根据在一个基于人群的IDDM登记处回顾性和前瞻性记录的数据计算得出的。1991年和1992年15岁以下儿童的患病率为每10万人中8.3例。1986 - 93年期间，15岁以下儿童IDDM的年龄标准化发病率为每年1.7/10万，95%置信区间为每年1.2 - 2.4/10万。男性的发病率为每年1.1/10万，女性为每年2.4/10万。
