Kadiki O A, Reddy M R, Marzouk A A
Benghazi Diabetic Clinic, Libya.
Diabetes Res Clin Pract. 1996 May;32(3):165-73. doi: 10.1016/0168-8227(96)01262-4.
The incidence of insulin-dependent diabetes (IDDM) and non-insulin-dependent diabetes (NIDDM) in Benghazi, Libya in the < 35-year age group during the period 1981-1990 are reported. Incidence data for IDDM were based on prospective registration of patients while incidence data for NIDDM were based on analysis of files. Case ascertainment of IDDM cases was estimated to be > 95%. Incidence of total diabetes (IDDM and NIDDM) (per 100000 population) was significantly higher in females (43.8; 95% confidence Interval (CI) 40.6-47.2) than in males (28.9, 26.6-31.3) (P < 0.001). The overall incidence rates of IDDM and NIDDM were 9.0 (CI, 8.1-10.0) and 27.3 (CI, 25.4-28.2), respectively. Rates of IDDM were 9.4 (CI, 8.1-10.9) among males and 8.5 (CI, 7.3-10.0) among females. Rates of NIDDM were 19.6 (CI, 18.1-22.2) among males and 35.3 (CI, 32.4-37.8) among females. IDDM patients showed a female predominance in the 0- to 14-year age range (P > 0.05) and a male predominance in the 15- to 34-year age range (P > 0.05). NIDDM showed equal incidence in males and females in the 0- to 14-year age range and twofold higher incidence in females than in males in the 15- to 34-year age group (P < 0.001). Yearly variation and seasonality of onset were not significant in IDDM cases (P > 0.05). Fifty-six percent of NIDDM cases were obese compared to only 6% of IDDM cases. The study revealed that diabetes mellitus is a common chronic disease in children and young Libyan Arabs. It has shown that NIDDM in Benghazi is twofold higher in females than in males in the 15- to 34-year age group. It has also shown that age per se is not a reliable criterion for the classification of diabetes into IDDM and NIDDM.
报告了1981 - 1990年期间利比亚班加西年龄小于35岁人群中胰岛素依赖型糖尿病(IDDM)和非胰岛素依赖型糖尿病(NIDDM)的发病率。IDDM的发病率数据基于患者的前瞻性登记,而NIDDM的发病率数据基于档案分析。IDDM病例的确诊率估计超过95%。女性的总糖尿病(IDDM和NIDDM)发病率(每100000人口)显著高于男性(43.8;95%置信区间(CI)40.6 - 47.2)(28.9,26.6 - 31.3)(P < 0.001)。IDDM和NIDDM的总体发病率分别为9.0(CI,8.1 - 10.0)和27.3(CI,25.4 - 28.2)。男性IDDM发病率为9.4(CI,8.1 - 10.9),女性为8.5(CI,7.3 - 10.0)。男性NIDDM发病率为19.6(CI,18.1 - 22.2),女性为35.3(CI,32.4 - 37.8)。IDDM患者在0至14岁年龄组中女性占优势(P > 0.05),在15至34岁年龄组中男性占优势(P > 0.05)。NIDDM在0至14岁年龄组中男性和女性发病率相等,在15至34岁年龄组中女性发病率是男性的两倍(P < 0.001)。IDDM病例的发病年份变化和季节性不显著(P > 0.05)。56%的NIDDM病例肥胖,而IDDM病例中只有6%肥胖。该研究表明,糖尿病在利比亚阿拉伯儿童和年轻人中是一种常见的慢性病。研究表明,在班加西15至34岁年龄组中,女性NIDDM发病率是男性的两倍。研究还表明,年龄本身并不是将糖尿病分为IDDM和NIDDM的可靠标准。