Svendsen O L, Hassager C, Christiansen C
Center for Clinical and Basic Research, Ballerup, Denmark.
Int J Obes Relat Metab Disord. 1994 Oct;18(10):692-8.
The aim of this work was to study the long-term effects of the addition of exercise to a short-term diet in overweight postmenopausal women. A follow up study was made of 118 overweight, postmenopausal women, who 6 months earlier had completed 12 weeks of randomized intervention (three groups: 4.2 MJ/d diet, 4.2 MJ/d diet with exercise, and controls). The following were measured: body composition and fat distribution (measured by dual-energy X-ray absorptiometry), resting metabolic rate, serum lipids and lipoproteins, blood pressure, and bone mineral densities. It was found that weight was still significantly reduced (by about 8 kg). HDL-C was significantly increased (10%), and triglycerides decreased (20%), whereas the initial reductions in total cholesterol and LDL-C had disappeared at the follow-up. The women from the former diet-plus-exercise group, who were current exercisers at the follow-up, had a significantly greater reduction in weight (10.9 vs 6.6 kg), fat tissue mass (10.0 vs 5.4 kg) and abdominal-to-total-body fat tissue mass (9.6 vs 4.7), and a significantly greater increase in the resting metabolic rate (11.1 vs 1.1 kJ/kg/d), as compared with the non-exercisers from this group. There were no major detrimental changes in total body, spinal, or forearm bone mineral density or in markers of bone turnover. The short-term dietary treatment in this study may have beneficial long-term effects on weight, fat tissue mass and cardiovascular risk factors with no additional benefits from added exercise, unless the exercise is continued.
这项研究的目的是探讨在超重绝经后女性中,短期饮食结合运动的长期效果。对118名超重绝经后女性进行了一项随访研究,这些女性在6个月前完成了为期12周的随机干预(分为三组:4.2兆焦/天饮食组、4.2兆焦/天饮食加运动组和对照组)。测量了以下指标:身体成分和脂肪分布(通过双能X线吸收法测量)、静息代谢率、血脂和脂蛋白、血压以及骨密度。结果发现体重仍显著降低(约8千克)。高密度脂蛋白胆固醇(HDL-C)显著升高(10%),甘油三酯降低(20%),而总胆固醇和低密度脂蛋白胆固醇(LDL-C)的初始降低在随访时消失。随访时仍在运动的原饮食加运动组女性,与该组不运动的女性相比,体重(10.9千克对6.6千克)、脂肪组织量(10.0千克对5.4千克)和腹部与全身脂肪组织量(9.6对4.7)的降低幅度显著更大,静息代谢率的升高幅度也显著更大(11.1千焦/千克/天对1.1千焦/千克/天)。全身、脊柱或前臂骨密度以及骨转换标志物均未出现重大有害变化。本研究中的短期饮食治疗可能对体重、脂肪组织量和心血管危险因素具有有益的长期影响,除非继续运动,否则增加运动并无额外益处。