Huang Z P, Liang K H
Department of Medicine, Affiliated Hospital, Medical College of Yichang, Hubei.
Zhonghua Nei Ke Za Zhi. 1994 Jun;33(6):373-5.
Acute and chronic effect of Radix Angelicae Sinensis (RAS) on serum gastrin levels in patients with cirrhosis were investigated. The results showed that after intravenous perfusion of RAS, serum gastrin levels of inferior vana cava, hepatic and peripheral veins were significantly decreased. After long-term administration of the agent, the level fell nearly to that of control subjects. It is suggested that the effect of reducing serum gastrin level by RAS may improve portal hemodynamics and be beneficial for portal hypertensive gastroduodenal mucosal lesions in cirrhosis.
研究了当归对肝硬化患者血清胃泌素水平的急慢性影响。结果显示，静脉灌注当归后，下腔静脉、肝静脉和外周静脉的血清胃泌素水平显著降低。长期给药后，该水平几乎降至对照组水平。提示当归降低血清胃泌素水平的作用可能改善门静脉血流动力学，对肝硬化门静脉高压性胃十二指肠黏膜病变有益。
