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表面活性剂系统:微乳液和囊泡作为药物递送载体

Surfactant systems: microemulsions and vesicles as vehicles for drug delivery.

作者信息

Lawrence M J

机构信息

Department of Pharmacy, King's College London, England.

出版信息

Eur J Drug Metab Pharmacokinet. 1994 Jul-Sep;19(3):257-69. doi: 10.1007/BF03188929.

Abstract

Although surfactants have been widely used as pharmaceutical adjuvants for many years, it is only relatively recently that their phase structures have been seriously considered as drug delivery vehicles per se. This review highlights the work to date investigating the potential of microemulsions as drug carriers and also reports on preliminary studies performed on the use of vesicles formed from nonionic surfactants.

摘要

尽管表面活性剂作为药物辅料已被广泛使用多年,但直到最近它们的相结构才被真正视为药物递送载体本身。这篇综述着重介绍了迄今为止关于微乳液作为药物载体潜力的研究工作,还报道了对由非离子表面活性剂形成的囊泡的初步研究。

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