利用多重聚合酶链反应和手工分型获得的关于三个四聚体短串联重复序列基因座（HUMTHO1、TPOX和CSF1PO）的中国人群数据。
Chinese population data on three tetrameric short tandem repeat loci--HUMTHO1, TPOX, and CSF1PO--derived using multiplex PCR and manual typing.
作者信息
Huang N E, Schumm J, Budowle B
机构信息
Criminal Investigation Bureau DNA Laboratory, Taipei, Taiwan, Republic of China.
出版信息
Forensic Sci Int. 1995 Jan 30;71(2):131-6. doi: 10.1016/0379-0738(94)01646-m.
Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci were determined in a Chinese sample population using multiplex polymerase chain reaction (PCR), electrophoresis of the PCR products in DNA sequencing gels and subsequent detection by silver staining. The loci are HUMTHO1, TPOX, and CSF1PO. All loci meet Hardy-Weinberg expectations. In addition, there is no evidence for association of alleles among the three loci. The allelic frequency data can be used in human identity testing to estimate the frequency of a multiple STR locus DNA profile in the Chinese population.
使用多重聚合酶链反应（PCR）、在DNA测序凝胶中对PCR产物进行电泳并随后通过银染检测，在中国样本群体中确定了三个四聚体短串联重复序列（STR）基因座的等位基因和基因型频率。这些基因座分别是HUMTHO1、TPOX和CSF1PO。所有基因座均符合哈迪-温伯格平衡预期。此外，没有证据表明这三个基因座之间的等位基因存在关联。等位基因频率数据可用于人类身份鉴定测试，以估计中国人群中多个STR基因座DNA图谱的频率。
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