Gusmão L, Prata M J, Amorim A
Instituto Antropologia, University Porto, Pr. Gomes Teixeira, Portugal.
Int J Legal Med. 1995;108(3):167-9. doi: 10.1007/BF01844832.
A population study was carried out on a random sample of 164 individuals from North Portugal using the short tandem repeat (STR) system hTPO (locus: 2p23-2pter). After electrophoresis, 7 alleles were identified of which 6 had been previously described and a new one, estimated to be 134 bp long. The observed genotype distribution is in Hardy-Weinberg equilibrium. In order to assess the forensic applicability of the system, namely for paternity investigations, 109 mother-child pairs were analysed. No exclusions were found and the observed distribution did not deviate from the expected. Since hTPO has a relatively high information content (PIC = 0.60; H = 0.65) this system can be very useful in paternity investigations.
利用短串联重复序列(STR)系统hTPO(基因座:2p23 - 2pter),对来自葡萄牙北部的164名个体的随机样本进行了群体研究。电泳后,鉴定出7个等位基因,其中6个先前已有描述,还有一个新的等位基因,估计长度为134 bp。观察到的基因型分布符合哈迪 - 温伯格平衡。为了评估该系统在法医方面的适用性,特别是在亲子鉴定调查中的适用性,分析了109对母婴对。未发现排除情况,观察到的分布与预期分布没有偏差。由于hTPO具有相对较高的信息含量(PIC = 0.60;H = 0.65),该系统在亲子鉴定调查中可能非常有用。