大肠杆菌NusG蛋白在体内和体外均能刺激转录延伸速率。
Escherichia coli NusG protein stimulates transcription elongation rates in vivo and in vitro.
作者信息
Burova E, Hung S C, Sagitov V, Stitt B L, Gottesman M E
机构信息
Institute of Cancer Research, College of Physicians and Surgeons of Columbia University, New York, New York 10032.
出版信息
J Bacteriol. 1995 Mar;177(5):1388-92. doi: 10.1128/jb.177.5.1388-1392.1995.
Abstract
The rate of transcription elongation in Escherichia coli was reduced when cells were depleted of NusG. In a purified in vitro system, NusG accelerated the transcription elongation rate. The stimulation of the rate of transcription elongation by NusG appears to result from the suppression of specific transcription pause sites.
摘要
当大肠杆菌细胞中缺乏NusG时，转录延伸速率降低。在纯化的体外系统中，NusG加速了转录延伸速率。NusG对转录延伸速率的刺激似乎是由于特定转录暂停位点的抑制。
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