Sattar A A, Schulman C C, Wespes E
Department of Urology, Erasme Hospital, University Clinics of Brussels, Belgium.
J Urol. 1995 Apr;153(4):1136-8.
Penile corporeal lacunar endothelium is active in the local neural control of corporeal smooth muscle relaxation by producing nitric oxide, a potent vasodilator neurotransmitter. Via computerized image analysis we quantified objectively the percentage of endothelial cells in corpus cavernosum tissues of potent and impotent men. Immunohistochemical staining factor VIII was used to identify the endothelial cells. Five normal potent men had a mean of 2.8% cavernous endothelial cells, compared to 2.4% in 12 patients with venous leakage and 2.8% in 10 with arterial disease. Objective quantification showed no difference in the numbers of cavernous endothelial cells between potent and impotent men.
阴茎海绵体腔隙内皮细胞通过产生一氧化氮（一种强效的血管舒张神经递质），在海绵体平滑肌舒张的局部神经控制中发挥作用。通过计算机图像分析，我们客观地量化了性功能正常和性功能障碍男性阴茎海绵体组织中内皮细胞的百分比。使用免疫组织化学染色因子VIII来识别内皮细胞。5名性功能正常的男性海绵体内皮细胞平均占2.8%，相比之下，12名静脉漏患者为2.4%，10名动脉疾病患者为2.8%。客观量化显示，性功能正常和性功能障碍男性之间海绵体内皮细胞数量没有差异。
