Kessaris D N, Wasserman P, Mellinger B C
Department of Urology, Long Island Jewish Medical Center, New Hyde Park, New York.
J Urol. 1995 Apr;153(4):1151-5.
A testis biopsy is used to assess quantitatively testicular spermatogenesis in infertile patients. Recently, several reports have used less invasive, percutaneous methods to obtain testis tissue. Percutaneous testis biopsies and touch imprints, immediately followed by open testis biopsies, were performed on 24 testes (19 patients) to ascertain whether they could provide the same histological information as an open biopsy. The technique of percutaneous testis biopsy using a core biopsy system is described. Comparison of the percutaneous and open biopsy histological diagnoses revealed a 95% correlation. The percutaneous method using 1 pass through the testis failed to provide adequate tissue in 2 of 24 patients. Touch imprints obtained by the percutaneous method also provided a 95% correlation compared with the open method (2 of 24 touch imprints were lost during processing and, thus, were not evaluated). Percutaneous testis biopsies and touch imprints provide adequate tissue for histological and cytological evaluation, with excellent correlation with biopsies obtained by the traditional open methods. Percutaneous testis biopsy and touch imprint may be performed in an office setting, thus obviating the need to perform an open biopsy in the operating room.
睾丸活检用于定量评估不育患者的睾丸生精功能。最近，有几份报告采用了侵入性较小的经皮方法获取睾丸组织。对24个睾丸（19例患者）进行了经皮睾丸活检及触摸印片，随后立即进行开放性睾丸活检，以确定它们是否能提供与开放性活检相同的组织学信息。描述了使用活检针系统进行经皮睾丸活检的技术。经皮活检与开放性活检组织学诊断的比较显示，二者的相关性为95%。在24例患者中，有2例患者采用经皮穿刺睾丸1次未能获取足够的组织。与开放性方法相比，经皮方法获得的触摸印片的相关性也为95%（24张触摸印片中，有2张在处理过程中丢失，因此未进行评估）。经皮睾丸活检及触摸印片可为组织学和细胞学评估提供足够的组织，与传统开放性方法获取的活检组织具有极好的相关性。经皮睾丸活检及触摸印片可在门诊进行，从而无需在手术室进行开放性活检。
