Hattori R, Kinukawa T, Ono Y, Kato N, Sahashi M, Yamada S, Mizutani K, Fujita T, Matsuura O, Ohshima S
Department of Urology, Okazaki City Hospital.
Nihon Hinyokika Gakkai Zasshi. 1994 Dec;85(12):1729-33. doi: 10.5980/jpnjurol1989.85.1729.
We described the clinical results and efficacy of laparoscopic pelvic lymphadenectomy for localized prostate cancer. This procedure was followed by radical prostatectomy, if metastasis was not found in frozen section. In the presence of positive nodes, optional treatment, such as TUR or castration, other than radical prostatectomy was performed. We performed laparoscopic lymphadenectomy on twenty seven patients between April 1992 and September 1993. They range from 52 to 78 years in age and consist of 4 patients with stage A2, 17 with stage B, and 6 with stage C. We dissected the obturator lymph nodes on bilateral sides. The average operating time was 162 minutes (range 86 to 320 minutes). The average number of nodes removed from the right side was 7.1 +/- 5.9 and 6.1 +/- 4.5 from the left side, which was comparable to the number of lymph nodes obtained by open dissection. Colon injury occurred in one patient, which was managed by laparotomy procedure. Nodal metastases were found in 6 patients by frozen section, and in 10 patients by permanent section. This discrepancy suggested that two-staged operation might be preferable for the localized prostate cancer. Six patients were given suitable therapies besides radical prostatectomy. Laparoscopic pelvic lymphadenectomy is a safe and useful procedure for prostate cancer, especially for the patients who are likely to have nodal metastasis.
我们描述了腹腔镜盆腔淋巴结清扫术治疗局限性前列腺癌的临床结果及疗效。若在冰冻切片中未发现转移,则在该手术后进行根治性前列腺切除术。若淋巴结阳性,则进行除根治性前列腺切除术之外的其他选择性治疗,如经尿道切除术(TUR)或去势。1992年4月至1993年9月期间,我们对27例患者实施了腹腔镜淋巴结清扫术。他们的年龄在52岁至78岁之间,其中4例为A2期,17例为B期,6例为C期。我们双侧解剖闭孔淋巴结。平均手术时间为162分钟(范围86至320分钟)。右侧平均切除淋巴结数为7.1±5.9个,左侧为6.1±4.5个,这与开放解剖获取的淋巴结数量相当。1例患者发生结肠损伤,通过开腹手术处理。冰冻切片发现6例有淋巴结转移,永久切片发现10例有淋巴结转移。这种差异表明,对于局限性前列腺癌,两阶段手术可能更为可取。6例患者除接受根治性前列腺切除术外,还接受了适当的治疗。腹腔镜盆腔淋巴结清扫术对于前列腺癌是一种安全且有用的手术,尤其适用于可能发生淋巴结转移的患者。