Funka-Lea G D, Schwaber J S
Neural Computahon Group, E. 1. DuPont de Nemours, Wilmington, DE 19880-0328.
J Neurosci Methods. 1994 Oct;54(2):253-60. doi: 10.1016/0165-0270(94)90197-x.
We describe the details and application of a digital brain atlas for the comparison and integration of graphical neurobiological data. The atlas consists of multiple sets of high-resolution video images acquired from histological tissue sections representing a 3-dimensional (3D) volume of an exemplar rat brain. Through an interactive graphical interface running on a standard computer workstation, experimental data is brought into register with the atlas. Once in the atlas, coordinate reference frame data can be compared, analyzed, and visualized in 3 dimensions. We demonstrate the validity and usefulness of the digital brain atlas with a series of results on the visceral neuraxis in the rat.
我们描述了一种用于图形神经生物学数据比较和整合的数字脑图谱的细节及应用。该图谱由多组高分辨率视频图像组成，这些图像是从代表一只典型大鼠脑三维（3D）体积的组织学切片中获取的。通过在标准计算机工作站上运行的交互式图形界面，实验数据与图谱进行配准。一旦进入图谱，坐标参考系数据就可以在三维空间中进行比较、分析和可视化。我们通过一系列关于大鼠内脏神经轴的结果证明了数字脑图谱的有效性和实用性。
