Chung Y, Park S E, Lee K, Yanagisawa Y, Spengler J D
Department of Preventive Medicine and Public Health, Yonsei University College of Medicine, Seoul, Korea.
Yonsei Med J. 1994 Dec;35(4):420-8. doi: 10.3349/ymj.1994.35.4.420.
Determinant factors for personal carbon monoxide (CO) exposures were sought in Korea, where CO poisoning has been a major public health problem due to coal briquette (Yeontan) combustion for space heating and cooking. Personal 24-hr CO exposures of 15 housewives were measured by CO passive samplers on 2 days of the week (Wednesday and Sunday). Blood samples were taken to measure carboxyhemoglobin (COHb) just after the exposure sampling. Average CO exposure and COHb level were 5.6 ppm and 2.4%, respectively. Personal CO exposures as well as COHb levels were significantly increased by the use of Yeontan, especially on a weekday. Carboxyhemoglobin levels were closely related to the time between blood collection and replacement of Yeontan: the closer the blood collection was to replace Yeontan, the higher the COHb levels were. Assuming a background COHb of 1.34%, COHb increased on average by 1.8% with a 24-hr personal CO exposure of 10 ppm. The relationship between CO exposure and COHb level was provided by simultaneous direct measurements in real environment, although a measurement of COHb at the end of exposure could not represent previous 24-hr exposure thoroughly.
在韩国，由于使用煤球（型煤）进行取暖和烹饪导致一氧化碳中毒成为一个主要的公共卫生问题，因此对个人一氧化碳（CO）暴露的决定因素进行了研究。通过CO被动采样器在一周中的两天（周三和周日）对15名家庭主妇进行了24小时的个人CO暴露测量。在暴露采样结束后立即采集血样以测量碳氧血红蛋白（COHb）。平均CO暴露量和COHb水平分别为5.6 ppm和2.4%。使用型煤会显著增加个人CO暴露以及COHb水平，尤其是在工作日。碳氧血红蛋白水平与采血时间和更换型煤的时间密切相关：采血时间越接近更换型煤的时间，COHb水平越高。假设背景COHb为1.34%，24小时个人CO暴露量为10 ppm时，COHb平均增加1.8%。尽管在暴露结束时测量COHb不能完全代表之前24小时的暴露情况，但通过在实际环境中同时进行直接测量，得出了CO暴露与COHb水平之间的关系。
