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[健康受试者近端食管的生理性反流(通过近端和远端食管同步pH监测进行评估)]

[Physiological reflux in proximal esophagus (assessment with simultaneous pH monitoring in proximal and distal esophagus in healthy subjects].

作者信息

Ruiz de León A, Sevilla-Mantilla M C, Pérez de la Serna J, Taxonera C, García-Cabezas J, Díaz-Rubio M

机构信息

Servicio de Aparato Digestivo, Hospital Universitario, San Carlos, Madrid.

出版信息

Rev Esp Enferm Dig. 1994 Dec;86(6):874-8.

PMID:7873260
Abstract

Two-level pH monitoring was performed for 24 hours in 20 healthy subjects to document the presence of reflux episodes and to obtain reference values for reflux studies. The pH probes were placed 5 and 20 centimetres above the LES by means of a manometric technique. Significant differences were found at these two levels. At the proximal esophageal level 18 of the 20 subjects had reflux episodes. Five centrimetres above the lower esphageal sphincter the total reflux time was 1.35%, 2.05% in the upright and 0.15% in the supine positions. At 20 centimetres level it was significantly lower: 0.5% the total percent time with pH below 4, 0.8% and 0% in the upright and supine positions respectively. The mean reflux time was about 40% of the distal value, but the same pattern of reflux was observed at two levels of the esophagus. This technique is useful in documenting the cephalad extend of GER and allows to identify normal GER patterns at different levels of the esophagus.

摘要

对20名健康受试者进行了为期24小时的两级pH监测,以记录反流发作情况并获取反流研究的参考值。通过测压技术将pH探头放置在LES上方5厘米和20厘米处。在这两个水平发现了显著差异。在食管近端水平,20名受试者中有18人出现反流发作。在食管下括约肌上方5厘米处,总反流时间在直立位为1.35%,在仰卧位为2.05%。在20厘米水平时显著降低:pH低于4的总时间百分比为0.5%,在直立位和仰卧位分别为0.8%和0%。平均反流时间约为远端值的40%,但在食管的两个水平观察到相同的反流模式。该技术有助于记录GER的向头端延伸,并能够识别食管不同水平的正常GER模式。

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