Johnson K R, Cook S A, Davisson M T
Jackson Laboratory, Bar Harbor, Maine 04609.
Mamm Genome. 1994 Nov;5(11):670-87. doi: 10.1007/BF00426073.
More than 150 individual members of 16 ribosomal protein multigene families were identified as DNA restriction fragments and genetically mapped. The ribosomal protein gene-related sequences are widely dispersed throughout the mouse genome. Map positions were determined by analysis of 144 progeny mice from both an interspecific (C57BL/6J x SPRET/Ei)F1 x SPRET/Ei and an intersubspecific (C57BL/6J x CAST/Ei)F1 x C57BL/6J backcross. In addition, 30 members of the multigene families encoding PGK1 ODC, and TPI, including five new loci for ODC and one new locus for TPI, were characterized and mapped. Interspecific backcross linkage data for 29 nonecotropic murine leukemia retroviruses endogenous to C57BL/6J mice are also reported. Transmission ratio distortions and recombination frequencies are compared between the two backcrosses.
超过150个属于16个核糖体蛋白多基因家族的个体成员被鉴定为DNA限制性片段并进行了基因定位。核糖体蛋白基因相关序列广泛分布于小鼠基因组中。通过对种间杂交（C57BL/6J×SPRET/Ei）F1×SPRET/Ei和亚种间杂交（C57BL/6J×CAST/Ei）F1×C57BL/6J回交产生的144只后代小鼠进行分析，确定了图谱位置。此外，对编码PGK1、ODC和TPI的多基因家族中的30个成员进行了表征和定位，其中包括ODC的5个新位点和TPI的1个新位点。还报告了C57BL/6J小鼠内源性的29种非嗜亲性鼠白血病逆转录病毒的种间回交连锁数据。比较了两个回交群体中的传递率畸变和重组频率。
