妥布霉素在尿路感染中的临床评估。
Clinical evaluation of tobramycin in urinary tract infections.
作者信息
Altucci P, Abbate G F, Gattoni A, Leonessa V
出版信息
J Infect Dis. 1976 Aug;134 Suppl:S139-41. doi: 10.1093/infdis/134.supplement_1.s139.
Twenty-one patients with urinary tract infections due to Pseudomonas and coli-form bacilli were treated with 80-120 mg of tobramycin per day in two daily doses. Of these patients, 14 (67%) were cured, one improved, three (14%) showed no improvement, and three (14%) showed a substitution of the original pathogen by another organism. Urine cultures demonstrated rapid sterilization in the cases in which patients responsed well, and long-term sterility persisted in at least 50% of the subjects.
21例由假单胞菌和大肠埃希菌引起尿路感染的患者，每天接受80 - 120毫克妥布霉素治疗，分两次给药。这些患者中，14例（67%）治愈，1例病情改善，3例（14%）无改善，3例（14%）出现原病原体被另一种微生物替代的情况。尿培养显示，反应良好的患者尿液迅速无菌，至少50%的患者保持长期无菌。
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