Bennet A H
J Infect Dis. 1976 Aug;134 Suppl:S156-7. doi: 10.1093/infdis/134.supplement_1.s156.
Twenty-five patients with severe urinary tract infections were treated with 3 mg of tobramycin/kg per day (given in two doses). Susceptible organisms were Escherichia coli, Proteus, Klebsiella, Pseudomonas, Streptococcus, and enterococcus. Clincal conditions in which treatment produced excellent bacteriological results included a wide range of urological disorders; the most common were pyelonephritis, cystitis, and epididymo-orchitis, Three patients had septicemia, and 12 had an infection that was the result of urinary tract obstruction requiring surgery.
25例严重尿路感染患者接受了每日3毫克/千克妥布霉素的治疗（分两次给药）。敏感菌包括大肠杆菌、变形杆菌、克雷伯菌、假单胞菌、链球菌和肠球菌。治疗取得优异细菌学效果的临床情况包括多种泌尿系统疾病；最常见的是肾盂肾炎、膀胱炎和附睾炎。3例患者发生败血症，12例患者的感染是由需要手术的尿路梗阻所致。
