Pfeiffer M, Griss P, Franke P, Bornscheuer C, Orth J, Wilke A, Clausen J D
Orthopdische Klinik, Philipps Universität, Marburg/Lahn, Germany.
Eur Spine J. 1994;3(1):8-16. doi: 10.1007/BF02428310.
In an experimental study with 18 minipigs, we have tried to establish a model for the standardized evaluation of mechanical, histological and radiological phenomena of degenerative and reparative processes within the lumbar motion segment. Comparing different operative techniques revealed that the intradiscal application of hyaluronic acid into the nuclear defect is likely to enhance the regeneration process. Using the measurement of disc compliance, a semiautomatic picture analyzer and a new semiquantitative disc score could make future studies more comparable. From this basis, the intradiscal application of hyaluronic acid deserves further evaluation.
在一项对18只小型猪的实验研究中，我们试图建立一个模型，用于对腰椎运动节段退变和修复过程中的力学、组织学和放射学现象进行标准化评估。比较不同的手术技术发现，向髓核缺损处椎间盘内注射透明质酸可能会促进再生过程。通过测量椎间盘顺应性、使用半自动图像分析仪和一种新的半定量椎间盘评分方法，未来的研究可能会更具可比性。基于此，椎间盘内注射透明质酸值得进一步评估。
