Baras L, Farber C M, Van Vooren J P, Parent D
Dept of Dermatology, Université Libre de Bruxelles, Erasme Hospital, Belgium.
Eur Respir J. 1994 Nov;7(11):2091-3.
Herpetic tracheobronchitis and pneumonia occur basically in immunodepressed patients, but have rarely been reported in patients with the acquired immunodeficiency syndrome (AIDS). Some large reviews on pulmonary manifestations in AIDS report a small number of herpetic pulmonary infections, without determining any prevalence of this particular viral involvement. Predisposing factors are alteration of cell-mediated immunity and invasive procedures (such as endotracheal tube use) in debilitated patients. The case we report illustrates the occurrence of a herpetic tracheitis in an HIV-infected patient with severe P. carinii pneumonia, needing systemic corticotherapy and mechanical ventilation. It illustrates the risk of dissemination of herpes simplex virus (HSV) from a herpetic stomatitis to the lower respiratory tract, even after the endotracheal cannula has been removed.
疱疹性气管支气管炎和肺炎基本发生于免疫抑制患者，但在获得性免疫缺陷综合征（AIDS）患者中鲜有报道。一些关于AIDS肺部表现的大型综述报告了少数疱疹性肺部感染病例，但未确定这种特定病毒感染的发生率。易感因素包括细胞介导免疫的改变以及虚弱患者的侵入性操作（如使用气管内导管）。我们报告的病例显示，一名患有严重卡氏肺孢子虫肺炎、需要全身皮质激素治疗和机械通气的HIV感染患者发生了疱疹性气管炎。这例病例表明，即使气管内插管已拔除，单纯疱疹病毒（HSV）仍有从疱疹性口炎播散至下呼吸道的风险。
