Ching C K, Lam S K
Department of Medicine, University of Hong Kong, Queen Mary Hospital.
J Gastroenterol Hepatol. 1994;9 Suppl 1:S4-7. doi: 10.1111/j.1440-1746.1994.tb01293.x.
Peptic ulcer disease is twice as common in people living in South China when compared with those in North China. However, the gastric cancer rate in North China is three times that of South China. The overall Helicobacter pylori prevalence rate is similar in North and South China populations and it is higher than Caucasians living in Western societies. However, there is a significantly higher prevalence of H. pylori seropositivity among those who live in the high gastric cancer areas of China. On the other hand, there is no significant difference in the H. pylori positive rate in the peptic ulcer disease patients between the two regions of China. Other permissive/associated co-factors in the development of peptic ulcer disease or gastric cancer remain unknown at this stage.
与中国北方人群相比，消化性溃疡病在中国南方人群中的发病率是北方人群的两倍。然而，中国北方的胃癌发病率是南方的三倍。中国北方和南方人群中幽门螺杆菌的总体流行率相似，且高于生活在西方社会的高加索人。然而，在中国胃癌高发地区人群中，幽门螺杆菌血清阳性率显著更高。另一方面，中国两个地区的消化性溃疡病患者中幽门螺杆菌阳性率没有显著差异。现阶段，消化性溃疡病或胃癌发生过程中的其他促成/相关协同因素仍不清楚。
