美沙酮维持治疗中的治疗社区方法（帕西奇项目）：一项开放性临床试验

Therapeutic community methods in methadone maintenance (Passages): an open clinical trial.

作者信息

De Leon G, Staines G L, Perlis T E, Sacks S, McKendrick K, Hilton R, Brady R

机构信息

Center for Therapeutic Community Research at National Development and Research Institutes, Inc., New York, NY.

出版信息

Drug Alcohol Depend. 1995 Jan;37(1):45-57. doi: 10.1016/0376-8716(94)01057-r.

DOI:10.1016/0376-8716(94)01057-r

PMID:7882873

Abstract

A non-random open clinical trial was conducted to determine whether a day-treatment program based on modified therapeutic community (TC) methods (Passages) produced better treatment outcomes for heroin addicts than did standard methadone maintenance therapy. Altogether, 327 methadone clients at two clinic sites were studied: 115 Passages members, and 212 comparison subjects. Compared to non-Passages clients, clients who voluntarily joined and remained in Passages for at least 6 months exhibited significantly larger reductions in cocaine use, heroin use, needle use, criminal activity, and psychological dysfunction. The present findings suggest that TC-oriented enhanced day-treatment can help methadone clients recover from drug abuse and adopt a prosocial lifestyle.

摘要

开展了一项非随机开放性临床试验，以确定基于改良治疗社区（TC）方法（“通道”项目）的日间治疗方案对海洛因成瘾者的治疗效果是否优于标准美沙酮维持疗法。总共对两个诊所的327名美沙酮治疗患者进行了研究：115名“通道”项目成员和212名对照对象。与非“通道”项目患者相比，自愿加入并在“通道”项目中至少持续6个月的患者在可卡因使用、海洛因使用、针头使用、犯罪活动和心理功能障碍方面的减少幅度显著更大。目前的研究结果表明，以治疗社区为导向的强化日间治疗可以帮助美沙酮治疗患者从药物滥用中康复，并采用亲社会的生活方式。