Bye P G
Acta Obstet Gynecol Scand Suppl. 1976;54:61-6. doi: 10.3109/00016347609156450.
An oral contraceptive containing D-norgestrel 150 mug. and ethinol oestradiol 30 mug. (Neovletta) was tested in 682 British women during more than 6,000 cycles. The pregnancy rate was 0.2 per 100 woman-years with the exclusion of pregnancies that followed admitted errors of tablet-taking, and 0.8 per 100 woman-years when they were included. 92.2 per cent of cycles were within 28 +/- 3 days. withdrawal-bleeding was missed in 3.3 per cent of cycles. Spotting occurred in 9.3 per cent of cycles and breakthrough bleeding in 5.8 per cent. Total bleeding averaged 4.71 days per cycle. Concurrent symptoms likely to be attributable to the pill were few and only 10.3 per cent of subjects withdrew because of them. It can be concluded that this formulation is extremely well tolerated and highly effective.
一种含有150微克炔诺孕酮和30微克炔雌醇的口服避孕药（诺美婷）在682名英国女性中进行了超过6000个周期的测试。排除因承认漏服药片后发生的妊娠，妊娠率为每100妇女年0.2例；若将这些妊娠包括在内，则为每100妇女年0.8例。92.2%的周期在28±3天内。3.3%的周期出现漏撤药性出血。9.3%的周期出现点滴出血，5.8%的周期出现突破性出血。总出血时间平均每个周期为4.71天。可能归因于该药的并发症状很少，只有10.3%的受试者因此停药。可以得出结论，这种配方耐受性极佳且效果显著。
