人类泡沫病毒与猿猴泡沫病毒的抗原关系。
Antigenic relationship of human foamy virus to the simian foamy viruses.
作者信息
Nemo G J, Brown P W, Gibbs C J, Gajdusek D C
出版信息
Infect Immun. 1978 Apr;20(1):69-72. doi: 10.1128/iai.20.1.69-72.1978.
Abstract
A foamy virus isolated by Achong et al. from a human nasopharyngeal carcinoma was studied to determine its antigenic relationship to the eight known simiam foamy viruses (SFV). Using reciprocal cross-immunofluorescent and cross-neutralization techniques, we found the human isolate to be closely related to SFV type 6. In a seroepidemiological survey, neutralizing antibody to the human foamy virus was not detected in the sera of animal caretakers or laboratory personnel who routinely handled a wide variety of nonhuman primates. We conclude that the human isolate most probably represents a variant strain of SFV type 6.
摘要
阿冲等人从一名人类鼻咽癌患者中分离出一种泡沫病毒，并对其与八种已知的猿猴泡沫病毒（SFV）的抗原关系进行了研究。采用双向交叉免疫荧光和交叉中和技术，我们发现该人类分离株与6型SFV密切相关。在一项血清流行病学调查中，在经常接触各种非人灵长类动物的动物饲养员或实验室人员的血清中未检测到针对该人类泡沫病毒的中和抗体。我们得出结论，该人类分离株很可能代表6型SFV的一个变异株。
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