Taylor-Robinson D, Gilroy C B, Horowitz S, Horowitz J
MRC Sexually Transmitted Diseases Research Group, St. Mary's Hospital, Paddington, London, UK.
Eur J Clin Microbiol Infect Dis. 1994 Dec;13(12):1066-9. doi: 10.1007/BF02111830.
Mycoplasma genitalium was sought in synovial fluids from 13 patients, of whom five had Reiter's syndrome, four had rheumatoid arthritis, and one each had systemic lupus erythematosus, psoriatic arthritis, rheumatic fever and undefined arthritis. The mycoplasma was detected by a PCR assay in the knee joint of a 25-year-old man with Reiter's syndrome, from whom urethral ureaplasmas were isolated and whose synovial fluid mononuclear cells responded to ureaplasmal antigens in a proliferation assay. Mycoplasma genitalium was also detected in the knee joint during an exacerbation of arthritis in a 58-year-old man who had had seronegative juvenile polyarthritis that had evolved to seronegative rheumatoid arthritis.
对13例患者的滑液进行了生殖支原体检测，其中5例患有赖特综合征，4例患有类风湿性关节炎，1例分别患有系统性红斑狼疮、银屑病关节炎、风湿热和未明确的关节炎。通过聚合酶链反应（PCR）检测，在一名患有赖特综合征的25岁男性的膝关节中发现了该支原体，从该患者尿道中分离出脲原体，其滑液单核细胞在增殖试验中对脲原体抗原产生反应。在一名58岁男性关节炎加重期间，其膝关节中也检测到了生殖支原体，该患者曾患有血清阴性幼年型多关节炎，后发展为血清阴性类风湿性关节炎。
