Grandhi A, Mujumdar A M, Patwardhan B
Indian Drugs Research Association, Pune.
J Ethnopharmacol. 1994 Dec;44(3):131-5. doi: 10.1016/0378-8741(94)01119-2.
The aqueous suspensions of roots of an Indian drug Ashwagandha and the Korean drug Ginseng were tested comparatively for 2 pharmacological activities, namely the anti-stress activity by the 'mice swimming endurance test' and anabolic activity by noting gain in body weights and levator ani muscle in rats. A significant increase in mice swimming time was shown by Ginseng (P < 0.001) and Ashwagandha (P < 0.01) as compared to the control group. Significant increase in body weights in the Ashwagandha treated group (P < 0.05) was better than Ginseng (P < 0.5). Gain in wet weights of the levator ani muscle were also significant in Ginseng (P < 0.001) and Ashwagandha (P < 0.01) treated groups, however, the weight gain of dried levator ani muscles showed comparable results for both these drugs (P < 0.01).
对一种印度药物阿育吠陀(Ashwagandha)和韩国药物人参的根的水悬浮液进行了两种药理活性的比较测试,即通过“小鼠游泳耐力试验”测定抗应激活性,以及通过记录大鼠体重增加和提肛肌变化来测定合成代谢活性。与人参对照组相比,人参(P < 0.001)和阿育吠陀(P < 0.01)均显著延长了小鼠游泳时间。阿育吠陀治疗组体重显著增加(P < 0.05),优于人参组(P < 0.5)。人参(P < 0.001)和阿育吠陀(P < 0.01)治疗组的提肛肌湿重也显著增加,然而,两种药物的提肛肌干重增加结果相当(P < 0.01)。