从一名57岁男性分离出的肺炎衣原体菌株的特性分析。

Characterization of a Chlamydia pneumoniae strain isolated from a 57-year-old man.

作者信息

Miyashita N, Kubota Y, Kimura M, Nakajima M, Niki Y, Soejima R, Matsumoto A

机构信息

Department of Microbiology, Kawasaki Medical School, Okayama, Japan.

出版信息

Microbiol Immunol. 1994;38(11):857-64. doi: 10.1111/j.1348-0421.1994.tb02138.x.

DOI:10.1111/j.1348-0421.1994.tb02138.x

PMID:7898384

Abstract

The isolation of Chlamydia pneumoniae, especially from elderly persons, is generally not easy. Recently, we succeeded in isolating a chlamydial strain, which was designated KKpn-15, from a 57-year-old man suffering from acute bronchitis. It was compared with well established strains of C. pneumoniae, C. trachomatis and C. psittaci, and its biological properties, such as the morphology of elementary bodies (EBs) and inclusions, and the immunochemistry of EB proteins, were investigated. Based on the results obtained in the present study, it was confirmed that the new chlamydial strain, KKpn-15, is a member of the C. pneumoniae strain and that the organisms of KKpn-15 are useful as an antigen for the serodiagnosis and epidemiology of C. pneumoniae infection.

摘要

肺炎衣原体的分离，尤其是从老年人中分离，通常并不容易。最近，我们成功地从一名患有急性支气管炎的57岁男性中分离出一株衣原体菌株，命名为KKpn-15。将其与已确立的肺炎衣原体、沙眼衣原体和鹦鹉热衣原体菌株进行比较，并研究了其生物学特性，如原体（EB）和包涵体的形态以及EB蛋白的免疫化学。根据本研究获得的结果，证实新的衣原体菌株KKpn-15是肺炎衣原体菌株的一员，并且KKpn-15的生物体可作为肺炎衣原体感染血清学诊断和流行病学的抗原。