Sugimura T, Miwa M
National Cancer Center, Tokyo, Japan.
Mol Cell Biochem. 1994 Sep;138(1-2):5-12. doi: 10.1007/BF00928437.
The early historical background of the discovery of poly(ADP-ribose) and the following development of science on poly(ADP-ribose) are reviewed. Fundamental knowledge on the natures of poly(ADP-ribose), poly(ADP-ribose) polymerase and enzymes degrading poly(ADP-ribose) are summarized with brief description on the methodology for their purification and characterization. Future prospect of research on biological significance of poly(ADP-ribose) has also been discussed briefly.
本文回顾了聚（ADP - 核糖）发现的早期历史背景以及随后关于聚（ADP - 核糖）的科学发展。总结了聚（ADP - 核糖）、聚（ADP - 核糖）聚合酶和降解聚（ADP - 核糖）的酶的基本性质，并简要描述了它们的纯化和表征方法。还简要讨论了聚（ADP - 核糖）生物学意义研究的未来前景。
