Kumar R, Yadav C L
Department of Veterinary Parasitology, CCS Haryana Agricultural University, India.
Trop Anim Health Prod. 1994 Nov;26(4):230-4. doi: 10.1007/BF02240389.
A survey was undertaken between March and September 1992 to assess the prevalence of fenbendazole resistance in sheep nematodes in 32 traditionally managed rural flocks and 22 intensively managed flocks on 3 farms. Fenbendazole, a commonly used anthelmintic was used at the recommended dose of 5 mg/kg body weight. Efficacy was determined on the basis of percentage reduction in strongyle faecal egg counts (FECR%) and larval cultures before and between 7 and 10 days after treatment. None of the traditionally managed rural flocks showed resistance and all had greater than 99% reduction in faecal egg counts after treatment. Of the 22 intensively managed flocks, however, 15 had slight fenbendazole resistance (between 60 and 90% reduction in egg counts) and 4 had severe resistance (less than 60% reduction).
1992年3月至9月期间进行了一项调查，以评估32个传统管理的农村羊群和3个农场22个集约化管理羊群中绵羊线虫对芬苯达唑的耐药性流行情况。芬苯达唑是一种常用的驱虫药，以5毫克/千克体重的推荐剂量使用。根据治疗前以及治疗后7至10天之间的粪便中圆线虫虫卵计数减少百分比（FECR%）和幼虫培养情况来确定疗效。所有传统管理的农村羊群均未显示出耐药性，且治疗后粪便虫卵计数减少均超过99%。然而，在22个集约化管理的羊群中，15个有轻微的芬苯达唑耐药性（虫卵计数减少60%至90%），4个有严重耐药性（虫卵计数减少少于60%）。
